TOP > AFFINIX Q4
We succeeded to develop multichannel QCM sensing system, AFFINIXQ4, allows individual 4 channel measurements simultaneously, contributes production of high quality data of many samples with control experiment. This model is suitable for many biomolecular interaction analyses and affinity and kinetic analysis such as protein-protein, protein-DNA, DNA-DNA, protein-polysaccharides and protein-lipid layer, and polymer, nanoparticle and material evaluations.
- Individual 4 channel measurements
- Higher throughput
- High sensitivity and low noise level
- Reduce sample consumption
- Affinity, binding constant measurements
- Kinetic and analysis within minutes
- Simple & easy operation
- Easy maintenance
- Low running cost
- Compact size
AFFINIXQ4 sensor
Cup-type QCM sensor for AFFINIXQ4 is easy to handle, suitable for immobilization of biological molecules. Standard surface of sensor is gold that is versatile surface for immobilization of biomolecules, we have many immobilization protocols of molecules and blocking protocols of non-specific bindings. We can offer special sensor surface (e.g. SiO2, TiO2 coating) upon your request, please contact us.
- High sensitivity 27 MHz frequency (fundamental resonance)
- Cup-type sensor cell assembled with acrylic cell and quartz sensor.
- Standard gold surface
- Metal coating sensors (e.g. SiO2, TiO2)
- Immobilization service of molecules
Application
- Non label, real time monitoring for molecular recognition or reaction monitoring
- Comparing experiments (specific or nonspecific ligand, analyte concentration, buffer condition, temperature. etc.)
- Analysis of binding constant (dissociation constant) and kinetic parameters
- Evaluation of affinity and kinetics for many molecules
- Screening of high affinity antibody to specific ligand
- Screening of high affinity ligand
- Aggregation monitoring
- Evaluation of polymer, thin film, nanoparticle, nanotube and other nanomaterials
- Interaction analysis between many molecules
- Long time measurement
- Build up the experimental procedures
- Measurements in crude solution
- Analysis of enzymatic reaction
Software (AQUA)
For Affinix series measurements, we provide the analytical software that enable to do following analysis easily.
- Equilibrium analysis (binding constant (Ka) and dissociation constant (Kd))
- Kinetic analysis (binding rate (kon) and off rate (koff))
